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Cetaphil Pro 4% Urea Smoothing Hydrating Lotion Cetaphil Pro 4% Urea Smoothing Hydrating Lotion contains bioactive ingredients that lock the moisture and soothe skin inflammation. It rejuvenates your dehydrated skin and gives it a healthy glow throughout the year. It softens your skin and eliminates dryness and roughness. It has skin-friendly ingredients and does not contain any harmful chemicals.